PharmiWeb

STEMart Enhances Medical Device Safety Testing with New In Vitro Micronucleus Test Service

STEMart, a US-based provider of comprehensive services for all phases of medical device development, has announced the availability of its robust In Vitro Micronucleus Test service to meet the ...
JSTOR Daily

The Force for Poleward Chromosome Motion in Haemanthus Cells Acts along the Length of the Chromosome during Metaphase but Only at the Kinetochore during Anaphase

This is a preview. Log in through your library . Abstract The force for poleward chromosome motion during mitosis is thought to act, in all higher organisms, exclusively through the kinetochore. We ...
Nature

Forbidden CIN

Aberrant mitosis results in chromosomal instability (CIN; the gain or loss of whole or large fragments of chromosomes), which is the main form of genome instability in cancers. Two papers provide new ...
Nature

Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements

Replication fork inactivation can be overcome by homologous recombination, but this can cause gross chromosomal rearrangements that subsequently missegregate at mitosis, driving further chromosome ...
The New England Journal of Medicine

Persistent Chromosomal Aberrations Following Radioiodine Therapy for Thyrotoxicosis

This study represents a prospective, serial investigation of the early and long-term chromosomal effects of relatively low doses of 131 I administered in the treatment of thyrotoxicosis. Dicentric ...
JSTOR Daily

Analysis of Radiation-Induced Micronuclei by Fluorescence In Situ Hybridization (FISH) Simultaneously Using Telomeric and Centromeric DNA Probes

B. M. Miller, T. Werner, H.-U. Weier and M. Nüsse Fluorescence in situ hybridization using simultaneously a combination of DNA probes for the telomeric hexamer repeat (TTAGGG) and the centromerically ...