CLINICAL differentiation of active from inactive acromegaly is often difficult. At the present time a diagnosis of active disease is often based on the tenuous correlation of certain signs and ...

THE association of hyperadrenocorticism with cancer has stimulated the curiosity of physicians for many years. Early work by Dobriner 1 suggested that the adrenal glands functioned differently both ...

We investigated the natural course of adrenal incidentalomas in 115 patients by means of a long-term endocrine and morphological (CT) follow-up protocol (median 4 year, range 1–7 year). At entry, we ...

Cushing's syndrome, characterised by chronic cortisol excess, represents a significant clinical challenge due to its varied aetiology, ranging from ACTH-dependent pituitary adenomas to adrenal ...