Mutation of HELLS (Helicase, Lymphoid-Specific)/Lsh in human DNA causes a severe immunodeficiency syndrome, but the nature of the defect remains unknown. We assessed here the role of Lsh in ...

The B-cell cytokine BlyS/BAFF (B-cell activating factor; also referred to as TALL-1, THANK or zTNF4) plays a critical role in B-lymphocyte development. Two receptors for the tumor necrosis factor ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 18 (May 3, 2022), pp. 1-12 (12 pages) B and T lymphocytes of the adaptive immune system undergo ...

Atypical lymphocytes are types of white blood cells that a person’s immune system produces. They help fight infections and diseases. High levels of atypical lymphocytes may indicate certain health ...