Adult cells can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only. This limits the potential use of adult cells for therapy.

Early mammalian development is a highly complex process involving elaborate and highly coordinated biological processes. One such process is zygotic genome activation (ZGA) which occurs following the ...

Totipotent cells own the highest differentiation potential of all cells. They can only be found shortly after fertilization in an early embryonic state and are capable of producing all cell types.

Mouse embryonic stem cells (ESCs) have emerged as ideal tools for developmental biology research due to their characteristics such as unlimited proliferation and pluripotent differentiation potential.

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only. This limits the potential use of adult cells for ...

Scientists have found a way to induce totipotency in embryonic cells that have already matured into pluripotency. This has great potential to improve cell engineering capabilities for regenerative ...

One of the most promising approaches to replacing sick or damaged cells with healthy cells is cellular reprogramming, whereby one cell type in our body converts to another cell type. Research has ...