The goal of this study was to investigate the potential roles of common genetic polymorphisms in CDA gene as prognostic factors in AML through the comparative analysis of 95 AMLs (50 NK-AMLs and 45 AK ...
Point mutations represent the majority of known pathogenic human genetic variants 1. Base editors enable the direct installation and correction of targeted point mutations in genomic DNA. These fusion ...
Cytidine 5′-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is analogous to the better-known ATP, but with cytidine as the base instead of adenine. It is a substrate in the ...
L'APOBEC est une famille d'enzymes qui a été découverte pour changer les cytidines en ARN ou en ADN. APOBEC est l'acronyme de l'anglais « apolipoprotein B mRNA editing enzyme, catalytic ...
At least five groups have independently invented a new class of CRISPR gene editing tools called dual base editors. The systems combine the functions and components of two CRISPR base editors, which ...
Papers from two independent groups suggest that a form of CRISPR gene editing, called base editing, causes a high number of unpredictable mutations in mouse embryos and rice. It’s not the first red ...
Nanjing Zhihe Pharmaceutical Technology Co. Ltd. has divulged cytidine derivatives reported to be useful for the treatment of viral infections.
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