A research team has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule. The breakthrough reveals how ...
The Enzyme-Substrate Complex The fleeting union of the enzyme and the substance on which it acts holds a key to our understanding of life processes. Many ingenious techniques are in use today to ...
Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...
For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...
Usually enzyme complexes make multistep processes easier by catalyzing sequential reactions in which the product of one enzyme becomes the substrate for the next. In a new finding, researchers report ...
Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...
The elucidation of the biosynthetic pathway of ipecacuanha alkaloids shows how two distantly related plant species could develop the same substance independently Plants produce an enormous abundance ...
Ongoing clinical research at UNC could lead to a first-of-its-kind enzyme replacement therapy for Hunter syndrome, an ...
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Two plant species 'invent' the same chemically complex and medically interesting substance
Plants produce an enormous abundance of natural products. Many natural plant products are ancestry-specific and occur only in certain plant families, sometimes only in a single species. Interestingly, ...
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