Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal ...

Elevation of the calcium concentration in human keratinocyte culture rapidly induces the redistribution of E-cadherin, P-cadherin, vinculin, β1 integrin, and desmoplakin to the cell-cell borders.

In many biological situations in vivo, including tissue shaping during morphogenesis, tissue repair and cancer invasion, cells do not move as single bodies but as a collective. Two main mechanisms ...

Within multicellular organisms, cells build connections with each other forming cell layers that cover the surfaces of tissues and organs and separate structures in the body. For example, the skin ...