EPFL scientists have now discovered that a DNA-sensing mechanism of the innate immune system - which is pivotal for the immediate defense against pathogens -- controls cellular senescence. The work is ...

Background Exacerbations are major causes of morbidity in individuals with chronic respiratory diseases such as chronic ...

A section of Goodsell et al.’s magnificent “Integrative illustration for coronavirus outreach” highlighting the packaging of the viral genetic material (in pink) by the scaffold “nucleocapsid protein” ...

Our immune system works to fight infections immediately, but also maintain long-term immunity. Two waves of protection help neutralize and eliminate disease, including the innate and adaptive immune ...

Group 2 innate lymphoid cells (ILC2s) of the immune system are involved in allergic diseases. But currently, therapy targeting ILC2s is not available. Now, researchers have identified a novel ...

Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...

Historically, inflammation against self was considered autoimmune, a concept that stems back to the seminal observations by Ehrlich, who described serum factors now known to be autoantibodies produced ...

Taken together, these advances suggest that part of age-related immune decline is driven by specific, potentially reversible ...