Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections. The nervous system works because neurons communicate across ...

A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected into presynaptic ...

Tomosyn's tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction, incluiding their ability to engage in a form of plasticity The ...

Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chat. The study helps find a better drug target for the ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...

Generations of studying the root cause of schizophrenia have largely converged around a single theory: the “dopamine hypothesis,” which postulates that a combination of genetic susceptibility, ...

Your brain is responsible for controlling most of your body’s activities. Its information processing capabilities are what allow you to learn, and it is the central repository of your memories. But ...

At 15 years old, Sammy considered himself an expert on cannabis. When I asked what he knew about how marijuana interacts with the brain, he confidently explained, “THC activates cannabinoid receptors ...

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...