Advances in genomics and transcriptomics continue to catapult basic and clinical research into a new era. A more comprehensive examination of genomic and transcriptional states allows for ...

Biostate AI was founded in 2023 by CEO David You Zhang, a co-founder and former CEO of NuProbe, the Houston and Shanghai-based genomics and molecular diagnostics company, along with CTO Ashwin ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

In total RNA sequencing experiments, many reads are not necessarily useful or desired for gene expression studies, including intronic reads from pre-mRNA or noncoding transcripts. Using target ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...