Now that human genome data have become available, it is increasingly important to elucidate the functions of proteins in living cells. Genetic approaches such as gene knockouts and RNA interference, ...
Chromophore-assisted laser inactivation (CALI) is a light-mediated technique that offers precise spatiotemporal control of protein inactivation, enabling better understanding of the protein's role in ...
Approaches based on nucleic acids such as gene knockouts, antisense and RNA interference to eliminate specific proteins intrinsically have limited temporal and spatial resolution, because they only ...
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