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  1. iPLEDGE REMS - Home

    The iPLEDGE PROGRAM REMS (Risk Evaluation and Mitigation Strategy) The iPLEDGE PROGRAM REMS is a safety program to manage the risk of isotretinoin’s teratogenicity and to minimize fetal …

  2. iPLEDGE REMS - Home

    The iPLEDGE PROGRAM REMS (Risk Evaluation and Mitigation Strategy) The iPLEDGE PROGRAM REMS is a safety program to manage the risk of isotretinoin’s teratogenicity and to minimize fetal …

  3. Jan 20, 2016 · pregnant patients 12 years of age and older with multiple inflammatory nodules with a diameter of 5mm or greater. The nodules may become suppurative or hemorrhagic. “Severe,” by …